Learn More: Ten Medications Older Adults Should Avoid or Use with Caution

This list is primarily based on the most common medication searches by U.S. users on the Liverpool COVID-19 Drug Interactions website. However, if Flexeril is prescribed, patients should carefully follow instructions written by their doctor, and shouldn’t take Tylenol unless their doctor tell them otherwise. Acetaminophen’s reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) can cause a potentially fatal, hepatic necrosis through the process of lipid peroxidation if acetaminophen is overdosed (more than 4g daily).

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Yes, prescription muscle relaxers can make you sleepy due to how they affect your central nervous system. Because of this, you should be cautious about operating heavy machinery, such as driving a car, or making important decisions while taking these medications. Each type of prescription muscle relaxer has different possible side effects. It’s important to talk to your provider or a pharmacist about possible side effects of the specific medication you’re taking or thinking of taking.

What Is Flexeril?

Flexeril is a strong muscle relaxant used with rest and physical therapy to treat muscle spasms. However, it is only for short-term relief from acute muscle pain and other skeletal conditions. It works by directly reducing muscle hyperactivity and decreasing the transmission of pain. These antidepressants have anticholinergic properties which can worsen memory, thinking or counteract the effectiveness of memory medications.

Current medications can’t cure Alzheimer’s disease or other dementias, but they might be able to slow it down and make it easier to live with. They may relieve symptoms related to memory, thinking, languageand other thought processes. In addition, they may also help with mood, agitation and other behavioral issues.

Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others.
Apart from those drugs stated above, other medications may interact with these drugs.
However, since Flexeril has properties that suppress pain, people may overuse it to amplify those feelings.
Ritonavir may also increase blood concentrations of certain concomitant medications.

From retail, clinical, program development, and administrative responsibilities, he’s your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. As mentioned, Flexeril and Tylenol are considered safe to use together. Their combined use won’t affect either drug and they don’t share similar side effects, for the most part. To view an interaction report containing 4 (or more) medications, please sign in or create an account.

Prescription muscle relaxers can be effective in treating spasticity, muscle spasms and muscle-related pain. But it’s important to weigh the possible risks of these medications, including their side effects and addiction potential. Be sure to talk to your healthcare provider about all the options available to treat your symptoms. Clinicians should consider the potential benefits of treatment with ritonavir-boosted nirmatrelvir, the potential risks of drug-drug interactions, and whether any risks related to drug-drug interactions can be safely managed. Clinicians should be aware that many commonly used medications can be safely coadministered with ritonavir-boosted nirmatrelvir despite its drug-drug interaction potential. Box 1 includes commonly prescribed medications that are not expected to have clinically relevant interactions with ritonavir-boosted nirmatrelvir.

The guidance in this document is based on the drug-drug interaction potential of the FDA-authorized 5-day course of ritonavir-boosted nirmatrelvir. M Ritonavir-boosted nirmatrelvir interacts with certain conjugated mAbs, such as ado-trastuzumab emtansine, mirvetuximab soravtansine, brentuximab vedotin, enfortumab vedotin, polatuzumab vedotin, and tisotumab vedotin. Before coadministering ritonavir-boosted nirmatrelvir and any of these conjugated mAbs, refer to the drug’s FDA prescribing information and consult with the patient’s specialist providers as needed. B Ritonavir-boosted nirmatrelvir interacts with certain conjugated mAbs, such as ado-trastuzumab emtansine, mirvetuximab soravtansine, brentuximab vedotin, enfortumab vedotin, polatuzumab vedotin, and tisotumab vedotin.

Drug Interactions

However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine’s side effects. Addiction Resource is an educational platform for sharing and disseminating information about addiction and substance abuse recovery centers. Addiction Resource is not a healthcare provider, nor does it claim to offer sound medical advice to anyone.

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Deviation from the recommended strategies may be appropriate in certain clinical scenarios. Ritonavir-boosted nirmatrelvir should not be given within 2 weeks of administering a strong CYP3A4 inducer (e.g., St. John’s wort, rifampin). Ritonavir-boosted nirmatrelvir is contraindicated in this setting because the delayed offset of enzyme induction may reduce the concentrations of nirmatrelvir and ritonavir, rendering the treatment ineffective against SARS-CoV-2. Tylenol-Codeine is a combination of acetaminophen 500 mg and codeine 8 mg that is used for relieving mild to moderate pain, fever reduce and as a cough suppressant.

Does Vyvanse interact with anything?

2,604 people who take Flexeril and Tylenol together, and have interactions are studied. There are no adequate studies of hydrocodone and acetaminophen in pregnant flexeril ultram women. There are no adequate studies of cyclobenzaprine in pregnant women. However, studies in animals suggest no important effects on the fetus.